PTE Retell Lecture真实讲座练习:基因组工程

在PTE中,无论是Summarise Spoken Text 还是 Re-tell Lecture的考题大都是从真实的讲座或者演讲中截取的,中间经常经常夹杂很多不同的环境音.很多同学都反映有时未必是听不懂,而是听不到. 鉴于此,墨尔本文波雅思PTE专门为大家总结了真实讲座的PTE练习音频,相比新闻音频来说,整体更加接近PTE考试的真题,内容方面,我们也会为大家提供考试中存在的近似题,最近我们会持续更新,敬请期待!


There is a long history actually of genetic modelling for science for using model organisms like mice to model human diseases to get some insights into these diseases. And really in the last 20 years that we had programmable nucleases of which crispers one kind of programmable nuclease. It’s always been kind of out of grasp of most biological scientists to use these tools easily. And the reason is that, just what you said, making proteins, protein engineering is hard, so imagine the genome, which like the human genome is 3 billion base pairs long. So every time you need to target a different region of the genome, you need to build a new protein and that, you know, you could just take my word for it that the bench when you do this, especially with the programmable nucleus, like zinc fingers or talents, is quite difficult, usually repetitive protein domains and rearranging them. It’s just not super easy. The quantum leap forward with crisper Cast Nine is that the nucleus component Cast Nine is actually generic. The thing that actually comes onto the DNA and cuts it and it’s guided to a specific location in that big genome by a small piece of DNA or RNA and one technology that we have really well done in our labs, actually we don’t even do it in our labs, we just sent it out to a company. And next day it just arrives at 2, but it’s overnight. You can get these these read, I can take that generic Cast Nine nucleus and move it around, so that’s really, I think if you, you know, take away one thing, it’s that compared to, you know, this field of genome area is actually existed for a long time. The real difference is it just got a whole lot easier in the last few years.

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